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Sophisticated Receptors For Next-Generation Cell Therapies.

Sophisticated Receptors For Next-Generation Cell Therapies. Sophisticated Receptors For Next-Generation Cell Therapies. Sophisticated Receptors For Next-Generation Cell Therapies.

Our modular receptors unlock a new era of safer, cost-effective, and potent treatments for cancer and autoimmune disease.

Introducing MARC: Modular Actuation Receptor Cells

Safe, Persistent, Potent

Despite enormous potential, CAR-T therapy remains limited by its high toxicity and poor therapeutic persistence, especially in the context of solid tumors.

 

MARC technology is the solution.

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The benefits of MARC

  • More persistent immune response prevents disease relapse
  • Complex and logic gated signalling: Modular receptors can be customized and optimized for specific applications
  • Compatible across immune cells: Functionality tested in T cells, NK cells, monocytes, macrophages, dendritic cells
  • Compatible with iPSC/ stem cells:MARC expressing stem cells/iPSCs can recreate the entire immune system 
  • Scalable and cost-effective

Backed by peer-reviewed science

Tual et al.  MARC, a novel modular chimeric antigen receptor, improves T cell-based cancer immunotherapies by preventing early T cell exhaustion and enhancing persistence. Published in JITC,  2025 

Link to publication

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